THESIS ON INDUCIBLE CLINDAMYCIN RESISTANCE

High prevalence of inducible clindamycin resistance among Staphylococcus aureus isolates from patients with cystic fibrosis. There was no significant difference in inducible clindamycin resistance regarding to methicillin susceptibility pattern. Quality control QC of the erythromycin and clindamycin discs was performed with S. Failure of clindamycin treatment of methicillin-resistant Staphylococcus aureus expressing inducible clindamycin resistance in vitro. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing; twenty-first informational supplement.

Gram-positive cocci are impor tant pathogens which can specially cause soft tissue and skin infection 1. Potential clindamycin resistance in clindamycin-susceptible, erythromycin-resistant Staphylococcus aureus: Indian J Med Microbiol ; Thirty three out of isolates of Staphylococcus aureus and 50 out of isolates of coagulase-negative staphylococci CoNS were subjected for D-zone testing. Amongst them, clindamycin has been considered as the preferred agent due to its excellent pharmacokinetic properties. J Lab Physicians ; 3: Thus, performing D-Zone testing is necessary to avoid misleading results which may cause treatment failure.

High prevalence of inducible clindamycin resistance among Staphylococcus aureus isolates from patients with cystic fibrosis. In such cases treatment with clindamycin may lead to clinical failure by developing constitutive resistant microorganisms 159. High prevalence of inducible clindamycin resistance among Staphylococcus aureus isolates from patients with cystic fibrosis. clindamycn

thesis on inducible clindamycin resistance

Clindamycin has good oral bio-availability and is helpful for outpatient therapy or as oral agent can be followed after intravenous therapy 2.

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Thus, performing D-Zone testing is necessary to avoid misleading results which may cause treatment failure.

Indian J Med Microbiol. Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci.

Diverse mechanisms can cause macrolide resistance 4. Inducible clindamycin resistance in staphylococci isolated from clinical samples.

Jundishapur Journal of Microbiology

Antimicrob Agents Chemother ; We did not observe any significant difference fhesis inducible clindamycin resistance and methicillin susceptibility pattern. Indian J Pathol Microbiol ; There was no significant difference in inducible clindamycin resistance regarding to methicillin susceptibility pattern.

Clin Infect Dis ; Open in a separate window. Frequency of different patterns of susceptibility to erythromycin and clindamycin in staphylococcus isolates.

Methicillin Susceptibility MS Pattern. Frequency of inducible clindamycin resistance in staphylococci regarding to methicillin susceptibility.

Inducible Clindamycin Resistance in Staphylococcus aureus Isolated from Clinical Samples

Incidence of constitutive rhesis inducible clindamycin resistance among hospital-associated Staphylococcus aureus. Also, we tried to ascertain the relationship between methicillin-resistant S. Both of these studies approximately supported our findings.

Incidence of constitutive and inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci in a community and a tertiary care hospital.

Inucible of a clinical failure. According to our findings, the frequency of erythromycin resistance was In a study by Dibah et al. Frequency of different patterns of susceptibility to erythromycin and clindamycin in staphylococcus isolates. Determination of antimicroial susceptibility patterns and inducible clindamycin resistance in Staphylococcus aureus strains recovered from southeastern Turkey. Considering the number of submitted samples, the most frequent inducible resistant microorganisms were retrieved from internal medicine wards.

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Jundishapur Journal of Microbiology

There is no substantial data regarding clindamycin prescription from India. Clinical and Laboratory Standards Institute; Parametric quantitative variables were compared using the independent sample t-test.

Thus, performing D-Zone testing is necessary to avoid misleading results which may cause treatment failure. However regarding wide spread use of this antibiotic, increasing number of oon isolates are being developed 17. Indian J Med Microbiol ; Although they are structurally different, their mode of action is similar 14.

Inducible clindamycin resistancein Staphylococci: The widespread use of this family of antibiotics has led to the development of resistant strains 7

thesis on inducible clindamycin resistance